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KMID : 0043319990220050515
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Archives of Pharmacal Research
1999 Volume.22 No. 5 p.515 ~ p.519
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Characterization of an Alkali-extracted Peptidoglycan from Korean Ganoderma lucidum
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Cheong Jae-Yeon
Jung Won-Tae
Park Won-Bong
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Abstract
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The biologically active peptidoglycan was purified form the alkali fraction of the fruiting bodies of Ganoderma lucidum and the composition of the peptidoglycan was investigated by conventional analyses. The alkali-extracted peptidoglycan showed differences in chemical compositions from the water-extracted. The alkali-extracted peptidoglycan contained 6.9% protein and 75.9% carbohydrates composed mainly of -glucose, mannose, and -glucose. The molecular weight range of the peptidoglycan was determined as 2,000 kDa-17 kDa. The peptidoglycan is considered to be a hybrid molecule of polysaccaride chains covalently bound as a side chain to the polypeptide core.
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KEYWORD
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Ganoderma lucidum, Fruiting body, Alkali extract, Peptidoglycan, Characterization
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